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. 2013 Nov 27;15(1):198–212. doi: 10.1208/s12249-013-0047-x

Fig. 4.

Fig. 4

a Apparent mass balance in the case of a 5% loss of parent and a 5% increase in degradation product peak area, using a charged aerosol detector (CAD). b Based on the added mass from lactose in the lactose adduct, a true mass balance using the charged aerosol detector would require a total peak area corresponding to 110% of the peak area of the initial (undegraded) pregabalin timepoint