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32 Full Factorial Design for the Preparation of NMS-loaded PLGA NPs, Providing the Two Levels for Each Evaluated Factor
| Factors | Levels | ||
|---|---|---|---|
| −1 | 0 | +1 | |
| Drug/polymer ratio (X1) | 1:10 | 1:15 | 1:20 |
| PVA % (X2) | 2 | 4 | 6 |
| Vitamin E TPGS % (X3) | 0.03 | 0.06 | 0.09 |
PVA poly(vinyl alcohol), TPGS d-α-tocopheryl polyethylene glycol 1000 succinate
