Skip to main content

View full-text article in PMC

. 2013 Nov 13;15(1):161–176. doi: 10.1208/s12249-013-0048-9

Table III.

Observed and Predicted Responses of Two Factors: Drug/Polymer Ratio (X1) and PVA Percentage Used (X2)

	Responses
	Observed values				Predicted values
	Q1^a (%)	Q2^a (nm)	Q3^a	Q4^a (mV)	Q1^a (%)	Q2^a (nm)	Q3^a	Q4^a(mV)
Factorial points
P1	89.54 ± 7.26	212.1 ± 2.01	0.101 ± 0.03	−26.8 ± 0.06	87.05	209.3	0.120	−26.9
P2	86.24 ± 9.49	231.3 ± 3.34	0.141 ± 0.02	−26.6 ± 2.48	93.63	231.8	0.120	−25.3
P3	84.94 ± 5.96	239.2 ± 2.22	0.226 ± 0.06	−25.0 ± 3.13	80.04	241.5	0.240	−26.2
P4	91.09 ± 4.69	211.9 ± 1.97	0.182 ± 0.01	−25.4 ± 2.72	93.94	219.7	0.140	−25.0
P5	72.86 ± 1.49	247.6 ± 2.78	0.223 ± 0.04	−28.3 ± 1.63	80.51	245.1	0.220	−25.9
P6	100.0 ± 16.02	275.2 ± 1.77	0.177 ± 0.04	−32.0 ± 1.88	99.65	270.2	0.200	−32.2
P7	96.7 ± 10.06	281.0 ± 1.29	0.199 ± 0.09	−33.6 ± 1.27	99.81	285.8	0.170	−32.2
P8	82.55 ± 0.61	288.5 ± 2.36	0.235 ± 0.01	−33.7 ± 0.40	79.80	288.7	0.230	−34.9
Center points
P9	100.0 ± 2.79	240.4 ± 2.35	0.117 ± 0.04	−24.1 ± 1.30	97.31	238.8	0.130	−24.2
P10	100.0 ± 0.45	238.1 ± 2.83	0.143 ± 0.08	−23.3 ± 1.07	97.31	238.8	0.130	−24.2
P11	98.21 ± 1.11	239.4 ± 1.65	0.128 ± 0.07	−22.3 ± 2.21	97.31	238.8	0.130	−24.2
P12	99.03 ± 2.43	240.5 ± 1.33	0.110 ± 0.06	−24.5 ± 1.46	97.31	238.8	0.130	−24.2
P13	99.78 ± 1.78	240.9 ± 1.89	0.133 ± 0.03	−24.0 ± 1.58	97.31	238.8	0.130	−24.2

^aThe values indicate mean ± standard deviation