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. 2013 Nov 13;15(1):161–176. doi: 10.1208/s12249-013-0048-9

Table IV.

Results of Model Coefficients and the Regression Analysis of Variance (ANOVA) of the Fitted Model for All Responses

Responses Model coefficients Regression analysis of variance
Factor Coefficients P value F P value R 2 Adj R 2 Adeq Precision
Q1 Intercept 97.3052 5.17 0.0265 0.7869 0.6346 5.607
X1 3.0883 0.1930
X2 −6.7133 0.0166
X12 −0.5881 0.8577
X22 −10.0831 0.0153
X1X2 −3.2125 0.2609
Q2 Intercept 238.7966 64.91 <0.0001 0.9789 0.9638 26.110
X1 27.0167 <0.0001
X2 12.6833 0.0002
X12 20.0121 0.0001
X22 −6.3879 0.0495
X1X2 −3.4500 0.1671
Q3 Intercept 0.1347 7.35 0.0104 0.8400 0.7257 7.332
X1 0.0238 0.0491
X2 0.0373 0.0074
X12 0.0141 0.3722
X22 0.0466 0.0161
X1X2 −0.0168 0.2148
Q4 Intercept −24.1828 13.91 0.0016 0.9085 0.8432 10.232
X1 −3.4833 0.0009
X2 −0.4667 0.4817
X12 −4.5603 0.0017
X22 −1.3103 0.1999
X1X2 −0.8750 0.2928
Y1 Intercept 88.5969 33.86 <0.0001 0.9603 0.9319 16.340
X1 −14.3733 0.0006
X3 8.8433 0.0081
X12 −30.2741 <0.0001
X32 −11.4341 0.0149
X1X3 0.8700 0.7776
Y2 Intercept 238.4276 400.30 <0.0001 0.9965 0.9940 68.307
X1 77.1000 <0.0001
X3 34.8000 <0.0001
X12 24.2035 <0.0001
X32 14.1035 0.0018
X1X3 7.8000 0.0144
Y3 Intercept 0.3704 137.33 <0.0001 0.9899 0.9827 36.092
X1 0.02150 0.0008
X3 0.0862 <0.0001
X12 0.0377 0.0003
X32 0.0357 0.0004
X1X3 −0.0003 0.4761
Y4 Intercept −29.1069 12.18 0.0024 0.8969 0.8233 11.116
X1 −1.1500 0.0183
X3 −1.5500 0.0044
X12 −0.7259 0.2313
X32 −1.7259 0.0169
X1X3 1.9250 0.0041