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. 2014 Jan 31;9(1):e87574. doi: 10.1371/journal.pone.0087574

Figure 5. HMGB-1 can affect retinal endothelial cell activity.

Figure 5

(A) Expression of CCL2 and CCL5 chemokines, IL-1β and IL-6 cytokines, as well as cell adhesion molecule ICAM-1 in HMGB-1-treated (5 and 10 µg/ml) and control (PBS-treated) retinal endothelial cells. Gene expression was assessed using quantitative RT-PCR in cells exposed to HMGB-1 or PBS after 24 hours (*P<0.05, **P<0.01, n = 6). (B) Comparative analysis of chemokine and cytokine expression in HMGB-1 treated retinal endothelial cells.