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. 2014 Jan 31;9(1):e87698. doi: 10.1371/journal.pone.0087698

Figure 1. Expression profiles of LIN28B and several miRNAs in embryonic tissue during normal placentation at early gestational periods.

Figure 1

Relative mRNA and miRNA levels were assayed in placental samples from normal pregnancies, obtained from women undergoing voluntary termination of pregnancy (VTOP) at gestational ages ranging from week-5 to week-9 after amenorrhea. Samples from week-5 and −6 of amenorrhea were grouped as ≤6-week gestational samples. Targets analyzed were: LIN28B (A), Let-7a (B), mir-132 (C), mir-145 (D) and mir-323-3p (E). Data are presented as mean ± SEM. Expression levels were quantitatively analyzed using the 2ΔΔCt method and were normalized to values from ≤6-week gestational samples. *, P<0.05; **, P<0.01; and ***, P<0.001 vs. values in ≤6-week gestational samples (One-way ANOVA followed by Newman-Keuls test).