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. 2014 Jan 31;9(1):e87698. doi: 10.1371/journal.pone.0087698

Figure 2. Altered expression of LIN28B and Let-7a in embryonic tissue from early ectopic pregnancies.

Figure 2

Relative levels of LIN28B mRNA (A) and Let-7 miRNA (B) were assayed in samples from VTOP controls and ectopic pregnancy patients. For presentation, the data were grouped in two gestation age ranges: ≤6-week vs. 7–9 week gestational samples. Data are presented as mean ± SEM. Expression levels were quantitatively analyzed using the 2ΔΔCt method and were normalized to values from ≤6-week VTOP (control) samples. Data were analyzed by two-way ANOVA, followed by individual Newman-Keuls tests; **, P<0.01 vs. corresponding values in control samples (effect of EP); a, P<0.01 vs. corresponding values in <6-week samples (effect of gestational age).