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. 2014 Jan 31;9(1):e87862. doi: 10.1371/journal.pone.0087862

Figure 1. Structure-based multiple sequence alignment of the regulatory domains of the three Psa solos with QS LuxRs and with the prototype of the PAB LuxR solos subfamily.

Figure 1

The residues belonging to Cluster 1, to Cluster 2 and Cluster 3 are highlighted in green, cyan and in orange, respectively. The 3D architecture of the boundaries of the ligand-binding site is schematized by r (roof), f (floor), p (proximal wall) and d (distal wall) and its tripartite topology by c (conserved core), s (specificity patch) and v (variable patch).