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. 2014 Jan 31;9(1):e87794. doi: 10.1371/journal.pone.0087794

Figure 1. CD8+ T-cells from IFN-OFF patients have an increased central memory compartment.

Figure 1

Memory status of CD8+ T-cells was determined by FACS-analysis using anti-CD45RA and –CCR7 antibodies. A) Examples of 3 IFN-OFF, 3 IFN-ON and 3 healthy controls. TCM, T central memory cells; TEM, T effector memory cells; TEMRA, T CD45RA+ effector memory cells B) The proportion of naïve CD8+ T-cells (CD45RA+CCR7+), C) CD8+ CD45RA+ effector memory T-cells (CD45RA+CCR7−), D) CD8+ central memory T-cells (CD45RA−CCR7+), and E) CD8+ effector memory T-cells (CD45RA−CCR7−) from all CD8+ T-cells. White dots represent pregnant patients in IFN-ON group (Table 1).