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Relationship between circulating levels of 4-hydroxynonenal bound to circulating thiol proteins (4HNE-P) and its precursor the n-6 polyunsaturated fatty acid linoleic acid in control and heart failure (HF) subjects. The dotted lines show the linear regression lines with 95% confidence intervals for all subjects in the control (C) and HF group. Control: Linoleic acid=1.2×4HNE-P+3691, P=0.38 (NS), HF: Linoleic acid=6.5×4HNE-P+2207, P=0.004.
