Figure - PMC

Skip to main content

An official website of the United States government

Here's how you know

Here's how you know

Official websites use .gov
A .gov website belongs to an official government organization in the United States.

Secure .gov websites use HTTPS
A lock ( ) or https:// means you've safely connected to the .gov website. Share sensitive information only on official, secure websites.

View full-text article in PMC

. 2014 Jan 15;4(1):130090. doi: 10.1098/rsob.130090

Search in PMC
Search in PubMed
View in NLM Catalog
Add to search

© 2014 The Authors. Published by the Royal Society under the terms of the Creative Commons Attribution License http://creativecommons.org/licenses/by/3.0/, which permits unrestricted use, provided the original author and source are credited.

PMC Copyright notice

Figure 3. — BR_187–385 adopts a fold that is distantly related to the MSCRAMM-typical DEv-IgG fold. Both CnaA-subdomains of Fap1 (PDB: 2X12) and GspB (3QD1), as well as the N3 subdomain of ClfB (3AU0), superimpose to BR_187–385 with r.m.s.d. values of 3.0, 3.2 and 3.9 Å, despite sequence identities of only 15%, 8% and 5% (see electronic supplementary material, figure S2 and supplemental movies), respectively. The fold of BR_187–385 is distantly related to the canonical DEv-IgG fold displayed by the N3 domain of ClfB. Topology diagrams of the DEv-IgG fold variants are designated and colour-coded according to [8,19,21].