Table 1.

Covariates assessed in the pharmacokinetic analysis

Covariate (unit)	Type
Actual dose (mg)	Continuous
Study (1 or 2)	Categorical
Age (years)	Continuous
Gender	Categorical
Race	Categorical
Weight at baseline (kg)	Continuous
Height (cm)	Continuous
Body surface area at baseline (m2)	Continuous
Body mass index at baseline (kg/m2)	Continuous
Ideal body weight at baseline (kg)	Continuous
Lean body weight at baseline (kg)	Continuous
Aspartate aminotransferase at baseline (U/L)	Continuous
Alanine aminotransferase at baseline (U/L)	Continuous
Bilirubin at baseline (mg/dL)	Continuous
Albumin at baseline (g/dL)	Continuous
Calculated creatinine clearance at baseline (mL/min)	Continuous