Table 1.
BMI and body composition and adipokines according to CHD and heart failure status.
| 18.5–25 | 25–29.9 | 30 + | p-trend | |
|---|---|---|---|---|
| Men with no CHD or heart failure (N = 3174) | ||||
| WC (cms) | 87.6 (6.54) | 98.3 (6.06) | 110.9 (8.22) | < 0.0001 |
| MAMC (cms) | 24.95 (1.88) | 26.81 (1.98) | 28.49 (2.23) | < 0.0001 |
| % low muscle mass | 56.7 | 20.9 | 7.8 | < 0.0001 |
| Adiponectin (μg/ml)* | 7.77 (5.14–12.32) | 6.48 (4.2–10.33) | 5.87 (3.89–9.25) | < 0.0001 |
| Leptin (ng/ml)* | 5.70 (3.7–8.35) | 9.68 (6.6–13.7) | 17.63 (11.4–23.1) | < 0.0001 |
| NT-proBNP (pg/ml)* | 87.4 (45–153) | 77.5 (38–146) | 85.6 (42–167) | 0.31 |
| Men with CHD and no heart failure (N = 860) | ||||
| WC (cms) | 88.1 (6.50) | 98.6 (5.99) | 112.1 (8.19) | < 0.0001 |
| MAMC (cms) | 24.5 (2.03) | 26.5 (2.00) | 28.2 (2.24) | < 0.0001 |
| % low muscle mass | 66.4 | 26.4 | 7.3 | < 0.0001 |
| Adiponectin (μg/ml)** | 8.24 (5.44–13.44) | 6.49 (3.98–10.89) | 5.81 (3.60–8.92) | < 0.0001 |
| Leptin (ng/ml)* | 6.75 (4.3–10.2) | 10.70 (7.2–15.9) | 18.73 (13–27.2) | < 0.0001 |
| NT-proBNP (pg/ml)* |
237.5 (112–511) | 196.4 (88.5–439.5) | 162.3 (71–326) | 0.0006 |
| Men with heart failure (N = 86) | ||||
| WC (cms) | 88.4 (7.40) | 99.3 (9.23) | 113.0 (9.86) | < 0.0001 |
| MAMC (cms) | 24.3 (1.60) | 26.2 (2.04) | 26.6 (2.56) | < 0.0001 |
| % low muscle mass | 73.9 | 31.1 | 27.8 | < 0.0001 |
| Adiponectin (μg/ml)* | 15.49 (12.35–19.69) | 6.69 (4.18–10.83) | 8.50 (5.78–16.53) | 0.01 |
| Leptin (ng/ml)* | 5.81 | 12.30 | 25.23 | < 0.0001 |
| NT-proBNP (pg/ml)* |
1236.5 (861–2753) | 278.7 (86.5–801) | 492.7 (332–1018) | 0.05 |
Mean (standard deviation) unless stated; * geometric mean and interquartile range.
Low muscle mass = lowest tertile MAMC.