Table 3.
Adiposity measures, muscle mass, adipokines, NT-proBNP and age-adjusted hazards ratio (95%CI) total mortality in men with no CHD or HF, men with CHD (no HF) and in men with HF.
| Men with no CHD or HF (n = 3174) | Men with CHD and no HF (n = 860) | Men with HF (n = 86) | |||||||
|---|---|---|---|---|---|---|---|---|---|
| Mortality rate/1000 per-yrs | 28.7 | 49.3 | 90.1 | ||||||
| BMI (kg/m2) | N | No of cases | Age-adjusted | N | No of cases | Age-adjusted | N | No of cases | Age-adjusted |
| < 25 | 990 | 304 | 1.00 | 229 | 119 | 1.00 | 23 | 19 | 1.00 |
| 25–29.9 | 1698 | 446 | 0.88 (0.76,1.02) | 440 | 178 | 0.74 (0.58,0.93) | 45 | 29 | 0.52 (0.29,0.94) |
| 30 + | 486 | 154 | 1.17 (0.97,1.42) | 191 | 81 | 0.88 (0.67,1.75) | 18 | 10 | 0.47 (0.22,1.01) |
| p-trend | P = 0.43 | P = 0.25 | P = 0.04 | ||||||
| WC | |||||||||
| < 94 | 1246 | 346 | 1.00 | 288 | 141 | 1.00 | 27 | 20 | 1.00 |
| 94–102 | 1057 | 280 | 0.99 (0.85,1.16) | 287 | 114 | 0.81 (0.63,1.04) | 28 | 17 | 0.51 (0.26,0.99) |
| > 102 | 871 | 278 | 1.23 (1.05,1.44) | 285 | 123 | 1.00 (0.78,1.28) | 31 | 21 | 0.63 (0.34,1.18) |
| p-trend | P = 0.02 | P = 0.67 | P = 0.23 | ||||||
|
Muscle Mass (MAMC) | |||||||||
| 1 (low) | 1057 | 398 | 1.00 | 287 | 158 | 1.00 | 30 | 21 | 1.00 |
| 2 | 1060 | 273 | 0.76 (0.65,0.88) | 286 | 113 | 0.74 (0.54, 0.94) | 27 | 17 | 1.16 (0.60, 2.26) |
| 3 (high) | 1057 | 233 | 0.71 (0.60,0.83) | 287 | 107 | 0.76 (0.59, 0.98) | 29 | 20 | 0.88 (0.48, 1.64) |
| p-Trend | P < 0.0001 | P = 0.03 | P = 0.68 | ||||||
| Leptin | |||||||||
| 1 (low) | 980 | 358 | 1.00 | 258 | 110 | 1.00 | 27 | 22 | 1.00 |
| 2 | 961 | 298 | 0.99 (0.84, 1.18) | 252 | 108 | 1.11 (0.85,1.45) | 26 | 15 | 0.49 (0.26,0.95) |
| 3 (high) | 966 | 165 | 1.21 (1.03,1.43) | 254 | 122 | 1.40 (1.08,1.81) | 27 | 16 | 0.35 (0.18,0.68) |
| p-Trend | P = 0.02 | P = 0.01 | P = 0.002 | ||||||
| Adiponectin | |||||||||
| 1 (low) | 1010 | 234 | 1.00 | 269 | 106 | 1.00 | 28 | 14 | 1.00 |
| 2 | 1011 | 276 | 1.13 (0.95,1.34) | 268 | 112 | 0.98 (0.75,1.29) | 27 | 19 | 1.60 (0.80,3.22) |
| 3 (high) | 1012 | 352 | 1.27 (1.07, 1.51) | 269 | 139 | 1.19 (0.92,1.54) | 27 | 21 | 2.30 (1.17,4. 50) |
| p-trend | P = 0.005 | P = 0.18 | P = 0.02 | ||||||
| NT-proBNP | |||||||||
| 1 (low) | 951 | 170 | 1.00 | 252 | 73 | 1.00 | 25 | 12 | 1.00 |
| 2 | 942 | 224 | 1.09 (0.89,1.34) | 251 | 98 | 1.26 (0.93,1.71) | 26 | 18 | 1.24 (0.58,2.65) |
| 3 (high) | 951 | 408 | 1.82 (1.50,2.20) | 253 | 165 | 2.38 (1.78,3.18) | 25 | 20 | 2.75 (1.32,5.72) |
| p-trend | P < 0.0001 | P < 0.0001 | P = 0.001 | ||||||
p-trend — test for trend across groups.