Table 1.
Properties of Hippocampal GCs In Vivo
| Anesthetized (mean ± SEM) | Awake (mean ± SEM) | |
|---|---|---|
| Resting potential | –71.9 ± 1.9 mV (n = 5) | –68.2 ± 1.5 mV (n = 8) |
| Membrane potential standard deviation | 1.2 ± 0.2 mV (n = 5) | 1.9 ± 0.2 mV (n = 8) |
| Input resistance | 151.0 ± 15.6 MΩ (n = 5) | 143.0 ± 10.8 MΩ (n = 8) |
| Membrane time constant τm | 15.9 ± 3.2 ms (n = 5) | ND |
| Mean frequency of EPSCsa | 15.7 ± 1.6 Hz (n = 15) | 15.1 ± 1.6 Hz (n = 13) |
| Individual EPSC peak amplitudeb | 8.76 ± 0.69 pA (n = 15) | 21.30 ± 2.4 pA (n = 13) |
| EPSC 20%–80% rise time | 2.24 ± 0.06 ms (n = 15) | 1.97 ± 0.06 ms (n = 13) |
| EPSC decay time constantb | 5.95 ± 0.26 ms (n = 15) | 3.84 ± 0.36 ms (n = 13) |
| EPSC-IEI distribution τ1 | 20.4 ± 2.4 ms (n = 15) | 27.1 ± 2.2 ms (n = 13) |
| EPSC-IEI distribution τ2 | 180.7 ± 24.3 ms (n = 15) | 148.7 ± 17.2 ms (n = 13) |
| EPSC-IEI distribution A1 | 68.2% ± 1.44% (n = 15) | 63.7% ± 3.0% (n = 13) |
| EPSC-IEI distribution A2 | 31.8% ± 1.44% (n = 15) | 36.3% ± 3.0% (n = 13) |
| Phase angle EPSCs versus LFP, theta range | NA | 321° ± 12° (n = 13) |
| Action potentials per burst | NA | 3.3 ± 0.9 (n = 3) |
| Phase angle action potentials versus LFP, theta range | NA | 284° ± 21° (n = 3) |
| Phase angle action potentials versus LFP, gamma range | NA | 340° ± 21° (n = 3) |
n indicates the number of experiments. ND, not determined (limited number of traces); NA, not applicable; IEI, interevent interval. See also Figure S2.
a
The supratheta range mean frequency of EPSCs reflects the occurrence of EPSC bursts.
b
Parameters that are statistically different between the two recording conditions (p < 0.05).