Table 5.
Inflammatory related serum markers for intervention versus control groupa
| Intervention | Control | ||||||||||||
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
|
| |||||||||||||
| Variable | Mean (M0) | SD | Mean (M3) | SD | Change score | Mean (M0) | SD | Mean (M3) | SD | Change score | Between group difference | P value | d |
| IL-6 (pg/ml) | 19.7 | 41.2 | 23.6 | 49.9 | 3.9 | 19.5 | 19.9 | 17.5 | 15.2 | −2.0 | 5.9 | 0.121 | 0.7 |
| IL-8 (pg/ml) | 7.3 | 2.3 | 6.7 | 2.6 | −0.6 | 7.7 | 1.7 | 7.5 | 3.4 | −0.3 | −0.3 | 0.758 | −0.1 |
| IL-10 (pg/ml) | 5.8 | 3.8 | 5.6 | 3.6 | −0.2 | 31.1 | 54.3 | 34.1 | 49.9 | 3.0 | −3.2 | 0.518 | −0.3 |
| TNF-alpha (pg/ml) | 9.6 | 5.6 | 7.0 | 3.3 | −2.6 | 9.6 | 10.7 | 7.7 | 8.9 | −1.9 | −0.8 | 0.690 | −0.2 |
| IL-6:IL-10 ratio | 3.34 | 5.30 | 2.64 | 3.10 | −0.7 | 1.35 | 1.33 | 1.53 | 2.29 | 0.18 | −0.88 | 0.333 | −0.4 |
| IL-8:IL-10 ratio | 1.58 | 0.74 | 1.64 | 0.76 | 0.06 | 1.09 | 0.76 | 1.39 | 1.30 | 0.30 | −0.24 | 0.531 | −0.3 |
| TNF alpha:IL-10 ratio | 1.95 | 1.13 | 1.94 | .98 | −0.01 | .99 | 0.89 | 1.42 | 2.20 | 0.43 | −0.44 | 0.416 | −0.4 |
| Leptin (ng/mL) | 46.5 | 29.1 | 43.9 | 27.8 | −2.6 | 34.4 | 23.1 | 40.8 | 32.2 | 6.4 | −9.0 | 0.031 | −1.0 |
| HMW adiponectin (ug/mL) | 8.8 | 5.4 | 8.7 | 5.2 | −0.01 | 9.0 | 6.2 | 7.6 | 5.5 | −1.4 | 1.41 | 0.361 | 0.4 |
| Total adiponectin (ug/mL) | 19.8 | 10.4 | 19.6 | 10.6 | −0.2 | 17.9 | 9.7 | 18.4 | 11.1 | 0.5 | −0.7 | 0.562 | −0.3 |
a
Data based on study participants completing both baseline and 3 month follow-up.
Abbreviations: M0, month 0 (baseline); M3, month 3; SD, standard deviation; d, effect size; IL, interleukin; TNF, tumor necrosis factor; HMW, high molecular weight