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. 2013 Jun 14;14(9):823–832. doi: 10.4161/cbt.25328

graphic file with name cbt-14-823-g4.jpg

Figure 4. Daunomycin-induced dissociation of histones from DNA measured by flow cytometer. (A–C) Concentrations of linker (H1) and core (H2B, H3, and H4) histones in daunomycin-treated cells after 4 h or 24 h incubation with the daunomycin. (D) Fluorescence of daunomycin bound to DNA, in fixed cells, as function of the drug concentration (4 h incubation)