Table 1.
EEG characteristics | Relevance to OSA | Normal amounts | |
---|---|---|---|
Wake | Low voltage, mixed frequency when eyes are open or alert; α activity (8–13 Hz) while relaxed with eyes closed | Typically increased in OSA | 15–20% of time in bed |
N1 | Predominantly low amplitude and relatively fast θ activity (3–7 Hz) accompanied by slow rolling-type eye movements | Typically increased in OSA | 4–6%, more in older patients |
N2 | Sleep spindles (12–14 Hz bursts lasting >0·5 s) and K complexes (large negative EEG wave followed immediately by a slower positive wave) on a background of low voltage, mixed frequency EEG | Typically increased in OSA | 50–65%, more in older patients |
N3 | Slow (<2 Hz), high amplitude (> 75 μV) EEG waves for more than half the epoch | Often absent or reduced in OSA, but associated with improved severity or complete absence of OSA when present | 15–20%, less in older patients |
REM | Low voltage, mixed frequency EEG with periodic runs of sawtooth waves accompanied by irregular movements of both eyes and low muscle tone | Often absent or reduced in OSA; often accompanied by worsening of respiratory events and more pronounced desaturation than the non-REM stages | 15–20% |
Arousals | 3–15 s return of waking or faster activity in the EEG; concurrent increase in EMG must be recorded in REM sleep | Commonly occur at the end of respiratory events, but also occur spontaneously or as a result of other stimuli (eg, leg movements) | 20 per h of sleep |
According to AASM scoring manual. REM=rapid eye movement. OSA=obstructive sleep apnoea. EEG=electroencephalogram. EMG=XXXX