Table 4.
Regression Model* to Predict Net Fluid Loss at 72 hours, including Clinical and Laboratory Covariates Assessed at or before Study Enrollment
Covariate | P value |
---|---|
Age | .02 (−) |
Sex | .07 (−) |
LVEF | .06 (+) |
NYHA class | .59 (−) |
Baseline global VAS | .51 (+) |
Baseline hemoglobin | .30 (−) |
Serum sodium | .45 (+) |
Baseline BUN | .24 (+) |
Baseline troponin I | .69 (−) |
Baseline NT-proBNP | .27 (+) |
Baseline cystatin C | .06 (−) |
Baseline creatinine | .32 (−) |
Furosemide dose | Interaction factor |
Continuous mode of therapy | Interaction factor |
Continuous mode × outpatient dose | .0028 (−) |
High initial IV diuretic dose | .0007 (+) |
198 patients had data available for this model.
Abbreviations: BUN, blood urea nitrogen; LVEF, left ventricular ejection fraction; NT-proBNP, N-terminal pro-B-type natriuretic peptide, NYHA, New York Heart Association; VAS, visual analog scale. The (+) and (−) after the P values signify the directionality of the regression