TABLE 2.

Prevalence of NPS by Primary Dementia Diagnosis and Overall Dementia Severity

	Primary Dementia Diagnosis					Dementia Severity (All Diagnoses Combined)
NPS, n (%)	Total (N = 3,768)	AD (n = 3,338)	DLB (n = 241)	bvFTD (n = 189)	p Value	Mild (n = 2,386)	Moderate (n = 951)	Severe (n = 431)	p Value
Agitation/aggression	1,519 (40)	1,320 (40)	99 (41)	100 (53)	0.001	826 (35)	451 (47)	242 (56)	<0.001
Depression/dysphoria	1,427 (38)	1,242 (37)	117 (49)	68 (36)	0.002	914 (38)	366 (39)	147 (34)	0.23
Anxiety	1,553 (41)	1,323 (40)	134 (56)	96 (51)	<0.001	939 (39)	434 (46)	180 (42)	0.004
Irritability/lability	1,522 (40)	1,329 (40)	103 (43)	90 (48)	0.08	929 (39)	426 (45)	167 (39)	0.006

Note. Neuropsychiatric symptoms (NPS) were reported by participants' caregivers/study partners using the Neuropsychiatric Inventory Questionnaire. For this analysis, NPS were scored as present or absent. Numbers in parentheses are percentages of participants in each diagnostic subgroup whose caregivers indicated the presence of the corresponding NPS.

p values were determined by a chi-square test, df = 2, for the associations of NPS with diagnosis type or severity

AD = Alzheimer's disease; DLB = Lewy body dementia; bvFTD = behavioral variant frontotemporal dementia.