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. 2014 Jan 15;28(2):198–210. doi: 10.1101/gad.228825.113

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© 2014 Gamalinda et al.; Published by Cold Spring Harbor Laboratory Press

This article is distributed exclusively by Cold Spring Harbor Laboratory Press for the first six months after the full-issue publication date (see http://genesdev.cshlp.org/site/misc/terms.xhtml). After six months, it is available under a Creative Commons License (Attribution-NonCommercial 3.0 Unported), as described at http://creativecommons.org/licenses/by-nc/3.0/.

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Figure 6. — Model for hierarchical assembly of yeast 60S ribosomal subunits. General principles of large subunit assembly. A representation of the 60S ribosomal subunit is illustrated, as viewed from the subunit interface. The 60S subunit is outlined in gray. The top panel shows sequential tightening of association of RPLs (circles). RPL groups are colored as in Figure 2, and stabilized association is indicated by a shift from transparent to solid circles. The bottom panel shows sequential stabilization of rRNA domains. 5.8S rRNA and domains I, II, III, IV, V, and VI are colored black, red, orange, yellow, green, blue, and purple, respectively.