Table 4.
Top ranking genes in MAPK pathway (WikiPathways) by various centrality measures.
| Gene | cd | cb | ce | c2s | c3s | crd | crb | cre | c2rs | c3rs |
|---|---|---|---|---|---|---|---|---|---|---|
| CASP* | 1 | 7 | 2 | 8 | 1 | 1 | ||||
| DUSP*(MKP) | 2 | 2 | 9 | 2 | 4 | |||||
| TGFBR1/2 | 3 | 10 | 3 | 10 | 7 | 5 | ||||
| IL1R1/2 | 4 | 1 | 1 | 4 | 1 | 5 | 1 | 5 | ||
| PPP3* | 5 | 4 | 9 | 8 | 7 | |||||
| K/N/MRAS | 6 | 6 | 5 | 3 | 6 | 9 | ||||
| PRKC*(PKC) | 7 | 6 | ||||||||
| GRB2 | 8 | 7 | 7 | 10 | 7 | |||||
| MAP3K1(MEKK1) | 9 | 2 | 4 | 2 | 8 | 4 | 3 | 2 | ||
| MAPK8-10(JNK) | 10 | 4 | 7 | 9 | ||||||
| TRAF2 | 3 | 6 | 3 | |||||||
| MAP3K7(MKK7) | 4 | 6 | 3 | |||||||
| MAP3K7IP1 | 5 | |||||||||
| RAC1/2,CDC42 | 8 | 5 | 10 | 3 | ||||||
| PTPN5/7,PTPRR(PTP) | 9 | 1 | 3 | 5 | 2 | 2 | 2 | 6 | ||
| MAP2K4(MKK4) | 10 | 10 | ||||||||
| MAPK1/3/4/6(ERK) | 3 | 1 | 5 | 1 | ||||||
| PTPN5 | 5 | 8 | ||||||||
| MAPK12-14(p38) | 8 | 10 | 8 | |||||||
| MAPK13 | 9 | |||||||||
| PTPN7 | 10 | |||||||||
| NRAS | 7 | 4 | ||||||||
| IKBKB/G,MAP3K14 | 9 | 10 | ||||||||
| MAPK1 | 8 | |||||||||
| KRAS | 8 | |||||||||
| MAPK10 | 9 |
Nodes that do not correspond to genes directly are omitted.