Table 5.

High betweenness edges in EGFR pathway.

Rank	eb (Edge)	Path	erb (Edge)	Path
1	GRB2–SOS1	Classical MAPK	GRB2–SOS1	Classical MAPK
2	SOS1–HRAS	Classical MAPK	SRC–PLCG1	Calcium
3	GRB2–REPS2		SRC–GAB2	SRC/GAB2/PI3K/AKT (Phagocytosis)
4	HRAS–RAF1	Classical MAPK	RAF1–MAP2K1	Classical MAPK
5	RAF1–MAP2K1	Classical MAPK	ASAP1–ARF6	PAG3/ARF6 (Phagocytosis)