Figure 2.

The three requirements of asymmetric cell division. For control of progeny proliferation, death, and differentiation during asymmetric cell division ACD, three requirements must be fulfilled; (1) an anchor to dictate the axis of polarity, in this case another cell; (2) the dividing cell is aligned along the axis of division, usually perpendicular to the anchor (perpendicular orientation shown by the alignment of mitotic spindle, red); and (3) that polarity of the protein (green) is maintained throughout division.