Figure 12.

Conservation and loss of motifs in NF-κB proteins. Conserved protein motifs were identified using MEME. Motifs (colored boxes) are drawn to scale, but the inter-motif regions (black lines) were altered to allow the motifs to align for ease of visualizing conservation in motif composition and order. The sequences included in the analysis were the NF-κB proteins of three cnidarians (Acropora millepora, E. lineata, N. vectensis) and one sponge (Amphimedon queenslandica) as well as the NF-κB1 and NF-κB2 proteins of Homo sapiens.