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Serum trastuzumab concentration–time profiles after subcutaneous (s.c.) or intravenous (i.v.) administration. (a) Individual serum trastuzumab concentration–time profiles after s.c. or i.v. administration of a 6 mg/kg dose to healthy subjects. (b) Median serum trastuzumab concentration–time profiles normalized by dose after s.c. administration of various doses in healthy subjects or patients with early breast cancer (EBC).
