Figure 1.

Tinnitus drug network. A drug–target network was generated with Cytoscape 3.0, by retrieving all drugs that produce tinnitus as side effect from SIDER and their targets from DrugBank and PDSP Ki. An edge was placed between a drug node and a target node if the protein is a target of that drug in the reference database. Target nodes were minimized to visualize the tinnitus drug space. Drugs were color coded according to first-level Anatomical Therapeutic Chemical Classification codes indicated in Supplementary Table S3.