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. Author manuscript; available in PMC: 2014 Feb 3.
Published in final edited form as: Mol Psychiatry. 2008 Mar 18;13(6):570–584. doi: 10.1038/mp.2008.25

Figure 1.

Figure 1

Results of single-marker association tests of case-control status for 492,900 SNPs. Panel A. shows the QQ plot (77) of the observed p-values, −log10 (p), versus those expected by chance, log10(iL+1), where p is the asymptotic p-value from the additive test that the SNP coefficient is zero, i is the rank for each SNP p-value (1=smallest, L=largest), and L is the number of SNPs. The dashed lines show the expected 95% probability interval for ordered p-values. Panel B depicts −log10 (p) for the 26,738 SNPs with p-values < 0.05 in the context of the human genome in order to make spatial clustering more evident.