TABLE 1.
Characteristics of 251 patients treated with upfront SRS*
| Variable | No. of Patients (%) |
|---|---|
| male sex | 121 (48) |
| median age in yrs (range) | 59.6 (15.7–93) |
| primary tumor | |
| non–small cell lung | 85 (34) |
| melanoma | 74 (29) |
| breast carcinoma | 40 (16) |
| renal cell carcinoma | 19 (8) |
| other | 33 (13) |
| baseline RPA class | |
| 1 | 24 (10) |
| 2 | 216 (86) |
| 3 | 11 (4) |
| baseline DS-GPA score | |
| 0–0.5 | 7 (3) |
| 1 | 33 (13) |
| 1.5 | 25 (10) |
| 2 | 63 (25) |
| 2.5 | 14 (6) |
| 3 | 68 (27) |
| 3.5–4 | 41 (16) |
| median total brain metastasis vol in cm3 (range) | 0.9 (0.3–22.9) |
| median no. of brain metastases (range) | 2 (1–9) |
| 1 | 104 (41) |
| 2–3 | 112 (45) |
| >3 | 35 (14) |
| SRS treatment | |
| Gamma Knife surgery | 223 (89) |
| LINAC-based radiosurgery | 28 (11) |
| salvage treatment | |
| none | 155 (62) |
| SRS | 56 (22) |
| WBRT | 31 (12) |
| neurosurgery alone | 4 (2) |
| neurosurgery & SRS | 3 (1) |
| neurosurgery & WBRT | 1 (<1) |
*
Values represent number of patients (%) unless otherwise indicated.