Table 1.

Effect of anticancer drugs on growth, viability and morphogenesis in Candida albicans

Serial number	Drug name	MIC50 § (μg/mL)	MFC50§ (μg/mL)		Concentration (μg/mL) of drugs required for inhibition of germ tubes
			2 h	4 h	50%	100%
1	Docetaxel	100	1600	1600	12.5	50
2	Paclitaxel	100	800	800	12.5	50
3	Vinblastine	100	600	600	NA	NA
4	Vincristine	50	400	400	12.5	> 50
5	Tamoxifen	100	NA	NA	NA	50
6	Bleomycin	50	800	800	NA	50
7	Doxorubicin	50	200	200	6.25	25
8	Daunorubicin	200	NA	NA	NA	25
9	5-flurouracil	100	NA	NA	25	50
10	Mitoxantrone	100	800	800	12.5	50
11	Mitomycin-C	800	NA	NA	12.5	50
12	Epirubicin	100	NA	NA	25	50
13	Dactinomycin	100	NA	NA	NA	50
14	Busulfan	50	400	400	12.5	50
15	Carmustine	100	NA	NA	12.5	50
16	Cyclophosmamide	25	800	800	6.25	50
17	Ifosfamide	100	NA	NA	12.5	50
18	Melphalan	200	600	600	12.5	50
19	Gemcitabine	200	NA	NA	25	50
20	Methotrexate	100	NA	NA	NA	25
21	Hydrooxyurea	800	NA	NA	NA	NA
22	Formestane	100	NA	NA	25	50
23	Etoposide	100	NA	NA	NA	25
24	Leuprolide	100	800	800	25	50
25	Dacarbazine	100	800	800	12.5	50
26	Carboplatin	50	600	600	NA	50
27	Cisplatin	50	800	800	12.5	50
28	Oxaliplatin	50	600	600	6.25	50
29	Leucovorine	NA	NA	NA	NA	NA
30	Irinotecan	50	800	800	25	50

^*MIC- Minimum Inhibitory Concentrations; MFC- Minimum Fungicidal Concentrations; NA- Not Achieved.

^§MIC values are taken from (Routh et al., 2011, Chemotherapy).