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. Author manuscript; available in PMC: 2014 Feb 3.
Published in final edited form as: Cancer. 2012 Feb 22;118(19):4652–4659. doi: 10.1002/cncr.27434

Table 4.

Univariate survival estimates following brain metastases

N Patients N Events Median survival (months) Lower 95% CI Upper 95% CI P
All 115 94 7.2 5.7 9.4
Age
 < 50 65 54 8.5 6.6 11.3
 ≥ 50 50 40 5.5 3.5 9.4 .11
Menopausal Status
 Pre 53 44 9.8 6.6 11.9
 Post 62 50 5.8 3.7 8.9 .13
Race
 White 82 69 8.9 5.8 10.8
 Black 15 11 7.7 4.1 8.1
 Other 18 14 5.5 2.8 19.8 .97
Stage
 I 16 13 7.7 5.7 18.4
 II 51 42 9.8 5.5 11.6
 III 48 39 5.8 3.4 6.9 .61
Nuclear Grade
 II 6 5 20.5 3.1 30.5
 III 107 88 6.9 5.7 9.4 .32
Lymphovascular invasion
 Negative 66 54 8.1 5.8 11.0
 Positive 46 38 6.4 4.2 9.7 .20
Breast surgery
 Breast conservation 42 32 7.7 4.6 10.8
 Mastectomy 68 59 6.9 5.4 9.7 .63
Adjuvant chemotherapy
 No 64 49 5.8 3.7 8.2
 Yes 51 45 8.9 6.9 11.9 .57
Taxane
 No 32 25 10.4 7.7 20.5
 Yes 83 69 6.4 4.1 8.5 .051
Anthracycline
 No 20 14 10.4 6.9 26.3
 Yes 95 80 6.5 4.6 8.5 .14
Adjuvant radiation
 No 38 35 6.7 3.2 11.0
 Yes 77 59 7.7 5.8 9.8 .61