Table 5.
Four independent linear regression analyses with SOC total and subdimension scores as dependent variables in patients with Crohn's disease (n = 238).
| Independent variables | SOC total score | Comprehensibility | Manageability | Meaningfulness | ||||
|---|---|---|---|---|---|---|---|---|
| β | P value | β | P value | β | P value | β | P value | |
| Step 1. | ||||||||
| Gender (female = 0) | 0.05 | 0.425 | 0.06 | 0.336 | 0.14 | 0.023 | −0.09 | 0.103 |
| Age in years | 0.11 | 0.070 | 0.11 | 0.096 | 0.06 | 0.359 | 0.06 | 0.333 |
| Education level (≤12 years = 0) | 0.09 | 0.144 | 0.04 | 0.590 | 0.13 | 0.045 | 0.07 | 0.251 |
| Work status (not working = 0) | −0.03 | 0.666 | 0.01 | 0.859 | ||||
| Marital status (not married/cohabitating = 0) | 0.10 | 0.090 | 0.09 | 0.174 | 0.14 | 0.023 | ||
| Current smoker (no = 0) | −0.06 | 0.305 | −0.03 | 0.643 | −0.11 | 0.063 | ||
| Explained variance (R 2) | 9.1% | 4.7% | 11.3% | 8.7% | ||||
| Step 2. | ||||||||
| HBAI | 0.00 | 0.990 | −0.01 | 0.866 | −0.01 | 0.856 | 0.02 | 0.694 |
| Disease duration in years | 0.08 | 0.186 | ||||||
| Adverse drug reaction (no = 0) | −0.08 | 0.157 | −0.11 | 0.075 | −0.10 | 0.104 | ||
| R 2 change | 3.1% | 2.3% | 2.8% | 2.3% | ||||
| Step 3. | ||||||||
| FSS-5 | −0.31 | <0.001 | −0.17 | 0.012 | −0.26 | <0.001 | −0.38 | <0.001 |
| R 2 change | 11.2% | 4.8% | 7.4% | 15.3% | ||||
| Step 4. | ||||||||
| GSE | 0.42 | <0.001 | 0.39 | <0.001 | 0.31 | <0.001 | 0.36 | <0.001 |
| R 2 change | 15.9% | 14.2% | 8.7% | 11.9% | ||||
|
| ||||||||
| Total R 2 | 39.3% | 26.0% | 30.3% | 38.2% | ||||
Abbreviations: β: standardized beta coefficient; HBAI: Harvey-Bradshaw activity index; FSS-5: Five-Item Fatigue Severity Scale; GSE: General Self-Efficacy Scale.
In addition to gender and age, variables that had a Pearson correlation coefficient with P < 0.10 in bivariate analyses were included in final regression models.