Table 1. patient and study characteristics for the 14 studies included in the meta-analysis.
| Author (Year) | Country | Study Design | Technology | Equipment | # Patients | % Male | % White | Age | Population | # Endoscopists | # Blinded pathologist | Dysp. AI | Total AI | Dysp. WLE | Total WLE | Biopsies AI | Biopsies WLE |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Canto, M. (2000) | USA | RCT (crossover) | MB | 1T-100 or 2T-100 (Olympus) | 43 | 74% | 95% | 60 (31 -70) | BE | - | Yes (2) | 19 | 43 | 12 | 43 | 563 | 385 |
| Grossner L. (2006) | Germany | RCT (cross-over) | MB | 450 HR (Fujinon) | 86 | 87% | - | 65 ± 8 | BE with HGD or AC | - | No (2) | 75 | 86 | 56 | 86 | 562 | 1217 |
| Horwhat, J. (2007) | USA | RCT (crossover) | MB | GIF 130 or 140, GIFQ 140: (Olympus) | 48 | 92% | 96% | 62 ± 11 | BE with HGD or AC | 48 | Yes (1) | 16 | 48 | 18 | 48 | 439 | 917 |
| Kara, M. (2005) | Nether-lands | RCT (crossover) | IC | GIF-Q240Z (Olympus) | 28 | 86% | - | 66 ±10 | BE ± dysp./neoplasia | 4 | Yes (2) | 11 | 14 | 9 | 14 | - | - |
| Ragunath, K. (2003) | UK | RCT (crossover) | MB | Olympus or Fujinon | 57 | 77% | - | 60 (31-85) | GERD or BE | 2 | Yes (2) | 26 | 57 | 23 | 57 | 651 | 618 |
| Fortun P. (2006) | UK | Post hoc analysis of images | AA | GIF Q240Z (Olympus) | 64 | 59% | - | 62 (26-83) | BE | 6 | Yes (1) | 8 | 62 | 2 | 62 | 368 | 357 |
| Wo, J. (2001) | USA | RCT (crossover) | MB | - | 47 | 89% | 93% | 57 ± 11 | GERD or BE | 3 | No (3) | 13 | 35 | 8 | 35 | 287 | 267 |
| Niepsuj, K. (2003) | Poland | Cross-sectional | AFI/LIFE | GIF-E; (Olympus) | 34 | 82% | 95% | 63 (40-77) | BE | 1 | - | 23 | 34 | 18 | 34 | 109 | 136 |
| Camus, M. (2009) | France | Prospective study (retrospective videos) | FICE/AA | EG 490 ZW5 (Fujinon) | 20 | 95% | 96% | 65 ± 15 | BE | 1 | No (3) | 7 | 18 | 1 | 18 | - | - |
| Curvers, W. (2010) | Nether-lands, US, UK | RCT (crossover) | ETMI | XGIF-Q240/GIF-FQ260FZ; (Olympus) | 87 | 82% | - | 67.1 ± 9.1 | BE with HGD/AC | 10 | Yes (5) | 81 | 87 | 69 | 87 | 11.5 | 14 |
| Curvers, W. (2008) | Nether-lands, US, UK | RCT (cross-sectional) | ETMI | XGIF-Q240FZ, (Olympus) | 84 | 83% | - | 67 ± 12 | BE ± Dysplasia | 5 | Yes (≥4) | 27 | 84 | 16 | 84 | - | - |
| Curvers, W. (2011) | Nether-lands | RCT (crossover) | AFI | XGIF-Q240/GIF-FQ260FZ; (Olympus) | 99 | 80% | - | 63 ± 10 | BE ± Dysplasia | 9 | Yes (9) | 60 | 99 | 54 | 99 | - | - |
| Wolfsen, H. (2008) | USA | RCT (tandem) | NBI | GIFH180; GIFQ160 (Olympus) | 65 | 82% | 93% | 66 | BE | 8 | - | 37 | 65 | 28 | 65 | Mean 4.7 | Mean 8.5 |
| Sharma, P. (2012) | US, Netherlands | RCT (crossover) | NBI | GIF-H180 (Olympus) | 123 | 93% | 97% | 63 (38 -85) | BE | - | Yes (1) | 40 | 123 | 35 | 123 | 442 | 934 |