Table 1.
MicroRNAs | Direct targets | Roles in GSC | Reference |
---|---|---|---|
miR-17-92 cluster | CTGF | Differentiation (-), proliferation (+), apoptosis (-) | Ernst et al. (2010) |
miR-451 | CAB39 | Differentiation (-), proliferation (+), apoptosis (-) | Godlewski et al. (2010b) |
miR-1275 | CLDN11 | Differentiation (-), proliferation (+) | Katsushima et al. (2012) |
miR-138 | CASP3, BLCAP, MXD1 | Differentiation (-), proliferation (+), apoptosis (-) | Chan et al. (2012) |
miR-137 | CDK6 | Differentiation (+), proliferation (-) | Silber et al. (2008) |
miR-34a | MET, NOTCH1, NOTCH2, CDK6 | Differentiation (+), proliferation (-), apoptosis (+) | Li et al. (2009b), Guessous et al. (2010) |
miR-302-367 cluster | CXCR4 | Differentiation (+), proliferation (-), invasion (-) | Fareh et al. (2012) |
miR-124 | SNAI2 | Differentiation (+), proliferation (-), invasion (-) | Xia et al. (2012) |
miR-204 | SOX4, EPHB2 | Differentiation (+), proliferation (-), invasion (-) | Ying et al. (2013) |
miR-128 | BMI1, SUZ12 | Differentiation (+), proliferation (-), radiosensitivity (-) | Godlewski et al. (2008), Peruzzi et al. (2013) |
(+) = increased, (–) = decreased.