Skip to main content
. Author manuscript; available in PMC: 2014 Dec 9.
Published in final edited form as: Chemistry. 2013 Nov 6;19(50):17043–17053. doi: 10.1002/chem.201301659

Figure 8.

Figure 8

1H-1H NOESY with 150 ms mixing time at 15 ºC in the backbone NH-CHα region of 1-ZF4. Rate of chemical exchange of backbone NH protons with water protons (δ 1H2O = 4.9 ppm, 15 ºC) was used to evaluate the degree of hydrogen bonding and consequently, structure. The position of the water peak is indicated by the blue dotted line. Peaks from the backbone NH of 1-ZF4 (as with apo-ZF4) exhibit detectable chemical exchange with water in comparison to those of Zn-ZF4 (SI Figure 9). This indicates a low degree of hydrogen bonding and from a disordered structure adopted by 1-ZF4.