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. Author manuscript; available in PMC: 2014 Feb 3.
Published in final edited form as: Mol Psychiatry. 2009 Aug 18;15(10):1034–1044. doi: 10.1038/mp.2009.78

Figure 1.

Figure 1

Chart illustrating the key Rho GTPases and their downstream effectors for actin and myosin activation leading to dendritic spine protrusion and transformation. RNA extracted from laser captured serotonin neurons was labeled and hybridized to the Rhesus Affymetrix GeneChip (n=2 animals/treatment) and the results were analyzed with GeneSifter. The genes in red increased 2-fold or greater and the genes in blue decreased 2-fold or greater with E or E+P treatment compared to ovariectomized placebo treated controls.