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. Author manuscript; available in PMC: 2014 Feb 3.
Published in final edited form as: Mol Psychiatry. 2009 Aug 18;15(10):1034–1044. doi: 10.1038/mp.2009.78

Figure 2.

Figure 2

Histograms illustrating changes in gene expression obtained with nested qRT-PCR on RNA extracted from laser captured serotonin neurons (n=3 animals/treatment). The Rho GTPases, RhoA, and Rac1 significantly increased with E alone (ANOVA p<0.0002 and 0.00115, respectively) whereas CDC42 increased with E and E+P (ANOVA p<0.05). Downstream effectors ROCK2 increased with E+P (ANOVA p<0.0047) whereas PIP5K and IRSp53 increased with E alone (ANOVA p<0.05 and #t-test p<0.0114, respectively).

The variance in IRSp53 in the E+P treated group was significantly different from the ovx group (+F test p<0.0028).

* p<0.05 different from ovx control with Student-Newman-Keuls posthoc pairwise comparison after ANOVA.