Figure 5. Type I IFN and TCR conjugation stimulate expression of LGP2 and RIG-I in CD8⁺ T cells.

CD8⁺ T cells were purified from WT mice through negative selection, and CD8⁺ T cells were stimulated with plate-bound anti-CD3 and anti-CD28. Parallel cultures were treated with IFN-β (100 IU/ml) for 24 hours. Cell lysates were collected and immunoblot analysis performed using the indicated antibodies. Data are representative of three independent experiments.