Table 1.
Virus subtype | ||||
---|---|---|---|---|
Mutations | B′ | Non-B′ | Total | Incidence (%) |
PIs | ||||
Major resistance mutations | ||||
V82A | 1 | 1 | 1.0 | |
Minor resistance mutations | ||||
I47M | 2 | 2 | 2.0 | |
A71T/V | 31 | 2 | 33 | 33.7 |
NRTIs | ||||
M41L | 1 | 1 | 1.0 | |
K65R | 1 | 1 | 1.0 | |
D67N | 2 | 2 | 2.0 | |
K70R | 1 | 1 | 1.0 | |
M184I | 2 | 2 | 2.0 | |
L210W | 1 | 1 | 1.0 | |
T215F/Y | 2 | 2 | 2.0 | |
K219E | 1 | 1 | 1.0 | |
NNRTIs | ||||
K103N/S | 5 | 5 | 5.1 | |
V106A | 1 | 1 | 1.0 | |
V179D | 1 | 2 | 3 | 3.1 |
Y188F/L | 2 | 2 | 2.0 | |
G190A | 1 | 1 | 1.0 | |
K238T | 1 | 1 | 1.0 | |
N348I | 1 | 1 | 1.0 | |
INIs | ||||
Minor resistance mutations | ||||
L68V/I/IM/LV | 40 | 40 | 40.8 | |
T97A | 1 | 1 | 1.0 | |
G163R | 1 | 1 | 1.0 |
Drug resistance mutations potentially conferring resistance to PIs, protease inhibitors; NRTIs, nucleoside reverse transcriptase inhibitors; NNRTIs, nonnucleoside reverse transcriptase inhibitors; INIs, integrase inhibitors.