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. Author manuscript; available in PMC: 2014 Feb 3.
Published in final edited form as: Arch Neurol. 2012 Oct;69(10):1303–1309. doi: 10.1001/archneurol.2012.465

Figure 4.

Figure 4

Comparison of interferon and interferon with statin therapy. The addition of a statin blocks interferon-beta therapy induction of P-Y-STAT1 (A) and myxovirus resistance 1 (MxA) and viperin proteins (B) in 14 patients with relapsing-remitting multiple sclerosis. Mononuclear cell lysates from no drug, statin alone, interferon-beta alone at 4 hours, and 4 hours of interferon-beta plus statin conditions are shown. Proteins were quantified with Western blots and normalized with actin. *P <.001 vs interferon-beta (paired t test). Error bars indicate SEM.