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. 2014 Jan 13;111(4):1304–1309. doi: 10.1073/pnas.1312369111

Table 1.

Summary of proteins associated with biogenic calcite

Organism Protein description Protein name Solubility Ref.
poly(glycine) and Asp/Glu rich regions, Cys MSI31 insoluble 21
Pinctada fucata (pearl oyster) Gly rich MSI7 insoluble 22
Pro/Ile/Tyr/Arg regions, Gly/Trp rich region, Asp rich region Prismalin-14 insoluble 23
Crassostrea nippona (Iwagaki oyster) acidic, highly phosphorylated, Asp/Glu/Cys rich MPP1 soluble 24
Crassostrea virginica (American oyster) highly phosphorylated, Asp/Ser/Gly rich None soluble 25
Adamussium colbecki (American scallop) highly phosphorylated, Asp/Ser/Gly rich None soluble 26
Patinopecten yessoensis (Yesso scallop) Ser/Gly/Asp rich, basic terminal sequence MSP1 insoluble 27
Pinna nobilis (Mediterranean fan mussel) Ala/Asp/Thr/Pro rich, Cys rich terminal sequence Calprismin soluble 28
Asp rich Caspartin soluble 28
Procambarus clarkia (crayfish) Glu/Ala rich GAMP insoluble 29
Gallus gallus (chicken) cysteic acid rich Ovotransferrin soluble 30
Anser anser (goose) Ala/Glu/Ser/Gly/Trp rich Ansocalcin soluble 31

Most calcite-extracted proteins are rich in carboxylate groups due to aspartic acid (Asp) and glutamic acid (Glu). Many are also phosphorylated or contain thiol groups in cysteine (Cys) residues. GAMP, gastrolith matrix protein.