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. 2014 Jan 13;111(4):1622–1627. doi: 10.1073/pnas.1314826111

Fig. 6.

Fig. 6.

ATF3 neuronal expression prolongs survival and delays motor deficits in the SOD1 mutant mice. (A) Hind limb grip strength analysis for WT, ATF3/WT, SOD1G93A, and ATF3/SOD1G93A mice. Data are mean ± SEM. *P < 0.05; ***P < 0.001 by repeated measures ANOVA with Bonferroni postanalysis (n = 30 mice per group). (B and C) ATF3/SOD1G93A mice display delayed onset of disease and prolonged survival (P = 0.0026 and P = 0.0013, respectively, by Kaplan–Meier log rank test for survival; n = 29 mice per group).