Table 1.

GRK3 IHC staining results on human prostate tissues

Tissue category	No.	Mean SI*	P value†
Prostate hyperplasia	41	4.0	<0.0005
Localized carcinoma	104	5.3	—
Castration-resistant carcinoma	33	5.1	—
Skeletal metastasis	13	4.6	—
Nonskeletal metastasis	33	6.8	0.001
Total	219	—	—

SI, staining index (range, 0–9).

*GRK3 expression.

^†By Kruskal–Wallis test, all carcinoma groups significantly stronger than hyperplasia. Nonskeletal metastasis strongest among carcinomas in a second Kruskal–Wallis test (hyperplasia excluded).