Fig. 2.

Core microRNA pathway components are required for NB maintenance in the mushroom body lineages. OK107-Gal4, UAS-mCD8::GFP-labeled WT (A), drosha^R662X (B), drosha^R1113X (C), drosha^∆,E859K (D), dcr-1^Q1147X (E), ago1^Q127X (F), and pasha^KO (G) adult MB neuroblast clones generated in newly hatched larvae and stained with anti-FasII antibodies. Arrowheads indicate α′/β′ neuron mistargeting and arrows indicate ɣ neuron overextension. (H) Average number of cells in adult MB clones of indicated genotypes. Differences between WT and all mutants are statistically significant (P < 0.0001). (Scale bar for A–G, 25 μm.)