FIG. 3.

Infection with SHIV-RT is blocked and HSV-2 reduced by MZC gel. (A) SHIV-RT viral loads of animals cochallenged with SHIV-RT/HSV-2 8 h after the last of 14 daily applications of either carrageenan (CG) control or MZC. The number of animals in each group is indicated. (B) Mean (±SEM) SHIV-RT viral loads of animals infected after application of CG (n=3) or no gel (n=4). (C) The percentage of animals infected by either SHIV-RT or HSV-2 after cochallenge without a gel or after application of CG or MZC. The numbers above each bar denote the number of infected animals over the total number cochallenged for each group. Fisher's exact test was performed to determine statistical significance.