Table 1.
Characteristics of case-control studies which are included in meta-analysis.
| First author, year of publication |
Country | Ethnicity | Participant origin | Average agea of | Sample size (cases/controls) |
No. of genotypes (cases/controls) |
|||
|---|---|---|---|---|---|---|---|---|---|
| Cases | Controls | AA | AB | BB | |||||
| Studies describing association between MBL codon 54 gene polymorphism and RVVC | |||||||||
| Babula, 2003 [14] | Latvia | Latvian | Hospital outpatient service | 27 (18–35) | 25 (18–35) | 42/43 | 13/39 | 26/4 | 3/0 |
| Liu, 2006 [17] | China | Chinese | Hospital outpatient service | 29 ± 6 | 31 ± 5 | 6/54b | 1/43 | 5/8 | 0 |
| Giraldo, 2007 [16] | Brazil | White/nonwhite | Hospital outpatient service | 31 (18–68)c | 33 (16–70) | 50/66 | 31/53 | 13/12 | 6/1 |
| Donders, 2008 [18] | Belgium | Caucasian, Asian | Hospital outpatient service | 36 ± 9 | 33 ± 10 | 109/55 | 69/48 | 36/7 | 4/0 |
| Wojitani, 2012 [15] | Brazil | White/nonwhite | Hospital outpatient service | 32 (18–50) | 30 (19–49) | 100/100 | 58/84 | 30/15 | 12/1 |
|
| |||||||||
| Studies describing association between MBL codon 54 gene polymorphism and VVC | |||||||||
| Liu, 2006 [17] | China | Chinese | Hospital outpatient service | 33 ± 8 | 31 ± 5 | 51/54c | 34/43 | 17/8 | 0 |
| Giraldo, 2007 [16] | Brazil | White/nonwhite | Hospital outpatient service | 31 (18–68)c | 33 (16–70) | 28/66 | 18/53 | 10/12 | 0/1 |
MBL: mannose-lectin binding; RVVC: recurrent vulvovaginal candidiasis; VVC: vulvovaginal candidiasis.
aExpressed as median with range or mean ± standard deviation, as reported in the original paper.
bFor three of 51 patients, genotypes were not determined because DNA could not be extracted from the respective samples.
cCalculated on the overall group of (R)VVC cases, as reported in the original paper.