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. 2014 Jan 22;7:43. doi: 10.1186/1756-3305-7-43

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Copyright © 2014 Arumugam et al.; licensee BioMed Central Ltd.

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. The Creative Commons Public Domain Dedication waiver (http://creativecommons.org/publicdomain/zero/1.0/) applies to the data made available in this article, unless otherwise stated.

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Vaccination with recombinant Bm-CPI-1 and Bm-CPI-2 does not confer protection against B. malayi infection in Mongolian gerbils but affects migration of worms and habitat selection. A) Total worm count. B) Distribution of worms in heart and lungs. C) Distribution of worms in lymphatic organs. Statistical significance was determined by unpaired t test using GraphPad Prism version 4.03, * denotes a significant difference between vaccinated group and alum adjuvant control, P ≤ 0.05. The line represents the median value.