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. 2013 Jul 30;8(3):441–449. doi: 10.4056/sigs.4027757

Table 4. Number of genes associated with the 25 general COG functional categories.

Code    Value    % of totala     Description
J    201    4.18     Translation
A    1    0.02     RNA processing and modification
K    452    9.41     Transcription
L    158    3.29     Replication, recombination and repair
B    1    0.02     Chromatin structure and dynamics
D    37    0.77     Cell cycle control, mitosis and meiosis
Y    0    0.00     Nuclear structure
V    57    1.19     Defense mechanisms
T    198    4.12     Signal transduction mechanisms
M    256    5.33     Cell wall/membrane biogenesis
N    142    2.96     Cell motility
Z    0    0.00     Cytoskeleton
W    0    0.00     Extracellular structures
U    166    3.46     Intracellular trafficking and secretion
O    153    3.18     Posttranslational modification, protein turnover, chaperones
C    275    5.72     Energy production and conversion
G    427    8.89     Carbohydrate transport and metabolism
E    487    10.14     Amino acid transport and metabolism
F    109    2.27     Nucleotide transport and metabolism
H    179    3.73     Coenzyme transport and metabolism
I    139    2.89     Lipid transport and metabolism
P    287    5.97     Inorganic ion transport and metabolism
Q    122    2.54     Secondary metabolite biosynthesis, transport and catabolism
R    549    11.43     General function prediction only
S    408    8.49     Function unknown
-    895    17.41     Not in COGs

a) The total is based on the total number of protein coding genes in the annotated genome.