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. 2014 Jan;58(1):1–10. doi: 10.1128/AAC.01790-12

TABLE 4.

Relation between ex vivo drug susceptibility at baseline and treatment outcome at day 42

Ex vivo agent tested pretreatment Treatment Treatment success
Recrudescencea
No. of tested ex vivo isolates IC50 ± SE (nM) No. of tested ex vivo isolates IC50 ± SE (nM)
DEAQ ASAQ 27 21.3 ± 2.7 8 31.8 ± 9.3
LUM AL 32 15.1 ± 2.1 2 9.6 ± 3.4
DHA ASAQ or AL 56 4.2 ± 0.4 9 3.6 ± 0.7
PYR SP 1 1,001 13 7,390 ± 2,340
a

Recrudescence defined by msp1 and msp2 analyses.