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Effect of treatment site and grooming on the efficacy of azithromycin cream treatments for prophylaxis against tick-transmitted spirochetes
| Treatment site or treatment | Grooming allowed | No. of spirochete-positive mice/no. of mice exposed | % protection |
|---|---|---|---|
| Bite site | Yes | 0/15 | 100a |
| Bite site | No | 1/18 | 92a |
| Distal | Yes | 0/10 | 100a |
| Distal | No | 0/12 | 100a |
| Control cream | NA | 7/10 | NAb |
P < 0.0001 compared to controls by Fisher's exact test.
NA, not applicable.
